Hi
I have a slightly complicated repeated measures 2 x 2 study design where 12 subjects have 4 sessions:
1. Placebo + no exercise
2. Placebo + exercise
3. Drug + no exercise
4. Exercise
Am keen to look at changes in RSNs between the groups
What is the most "preferred" approach for this? i.e.
1. Group each session from each of the 12 subjects (i.e. 12 x 4 data sets) and use these to create my templates.
Then run a dual regression for each of the sessions against the templates
Then do subtractions between the D_Rs to look for differences
2. Group only the placebo/no exercise subjects to form the templates (as this is effectively a "control" group)
Then run the d_r as above
Can I ask what people think?
Thank you
Monty
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