Hi All,
I have data acquired with multiple b-values and I use topup with default parameters (specifically --scale=0). There appears to be a global scaling applied to the data and the scaling is not the same across b-values. I dealt with this by dividing the unwarped image by the mean of the unwarped image and multiplying by the mean of the original image. This normalization appeared to "fix" the problem, but I'm not sure how accurate it is. Does anyone know how the scaling is computed?
thanks!
jack
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