Hello everybody
Why sometimes same enzyme of a homologous series from different
organism show different affinity towards type of metal ion for its
activity..Lets say threonine dehydratase from H pylori show maximum
activity with Mg2+ as a cofactor while the same enzyme from Entamoeba
histolytica showed maximum activity with Zn2+..while in others it is
Mn2+..What could be the chemical or physical phenomenon for this
difference ??..Can anybody suggest or name some good paper for this
explanation..
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Regards
Faisal
School of Life Sciences
JNU
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