Dear Jacob,
6 phosphogluconate dehydrogenase :-
See Chen et al 2010 J Struct Biol 169,25-35
and for which enzyme there has been a longstanding interest in the protein dynamics and studies linking with diffuse X-ray scattering: see Biochem Soc Trans (1986) 14, 653-655.
Best wishes,
John
Prof John R Helliwell DSc
On 27 Feb 2014, at 19:43, "Keller, Jacob" <[log in to unmask]> wrote:
> Dear Crystallographers,
>
> Does anyone know of good examples of large, reversible conformational changes occurring between ligand-free and -bound states? Could also be a non-relevant molecule binding, like sulfate or something inducing dubiously -relevant changes. I already know of the calmodulin and periplasmic binding protein families, but does anyone know of others out there?
>
> All the best,
>
> Jacob Keller
>
> *******************************************
> Jacob Pearson Keller, PhD
> Looger Lab/HHMI Janelia Farms Research Campus
> 19700 Helix Dr, Ashburn, VA 20147
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