Dear Naoki,
for elderly subjects or even Alzheimer's patients I only use the standard DARTEL template that is used by VBM8. Only for children data I create a customized template. However, this is purely based on my personal experience and if you have a large, representative sample of elderlies you will make nothing wrong by creating your own DARTEL template.
You can create this template with the DARTEL toolbox by using the segmentations either from SPM12b or VBM8. I would strongly recommend to use rather the segmentation of SPM12b than SPM8 because there is a large improvement in segmentation quality especially for subjects that deviate from healthy control subjects. In VBM8 you can also export the segmentations to DARTEL via the option "DARTEL export| affine".
Best,
Christian
On Tue, 7 Jan 2014 10:22:48 +0000, Naoki Hirabayashi <[log in to unmask]> wrote:
>Dear Experts,
>
>I'd like to know which algorithm is suitable for voxel based morphometry of the elderly, SPM8 or VBM8 algorithm?
>
>In my understanding an already existing Dartel template in MNI space is used in VBM8 procedure.
>
>In SPM8 procedure, dartel template which is created from all subjects is used.
>
>
>Any suggestion would be highly appreciated.
>
>
>Thank you so much,
>Naoki Hirabayashi
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