Hi,
I am facing a problem in refining one of my structures. With every
refinement the Rwork is going down. However, the Rfree is stuck and is
not going down with refinement. I have already solved the structure
without the co-factor bound. This structure is with the co-factor
bound. Can anyone suggest the reason for the Rfree getting stuck?
Thanks
--
Nazia Nasir
PhD Scholar
Protein Crystallography Lab
National Institute of Immunology
New Delhi
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