Dear SPM-experts
I am currently working on a longitudinal analysis of VBM/DARTEL in SPM12b. My MRI series consists of three timepoints, there's a surgical intervention between t1 and t2. My main interest lies in grey/white matter volume changes between t1, t2 and t3 - focusing on the contralateral hemisphere. as ipsilateral changes are trivial. The lesion is quite homogenous among all subjects.
Although I am familiar with VBM/DARTEL, I find it extremely difficult to get any information on the exact registration procedures. some previous posts dealt with 2 timepoints or similar scenarios, however, mostly with healthy subjects.
I am not sure whether to use a common, preoperative template for all registration purposes or if a specific template per timepoint / mean / xxx would make more sense.
Would appreciate your advise!
Niels
|