The amylase creatinine clearance ratio used to be in vogue to differentiate hyperamylasaemia due to acute pancreatitis from other causes, the ACCR is > 5% in acute pancreatitis and less than 5% in other conditions associated with hyperamylasaemia. Also in late presenting acute pancreatitis patients, urinary amylase tend to stay elevated for >72 hours.
Regards
Mohammad
Dr. M A Al-Jubouri, MB ChB, MSc, EurClinChem, FRCP Edin, FRCPath
Consultant Chemical Pathologist
--------------------------------------------
On Wed, 26/6/13, Colley, Michael <[log in to unmask]> wrote:
Subject: Re: Urinary amylase
To: [log in to unmask]
Date: Wednesday, 26 June, 2013, 14:45
Your mailing stimulated me to survey
our usage.
Samples NEQAS
2010
13 33
2011
1
33
2012
6
36
2013(so far) 4
15
------ -----
24
117
Of these there have been 3 high urine amylase values, of
which 2 had elevated serum amylase. The other had no serum
amylase associated with it.
On the other hand there were 5 elevated serum amylases with
normal associated urine amylase.
As you say, is this a worthwhile test?
Michael
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]]
On Behalf Of Woodrow Iain
Sent: 26 June 2013 12:10
To: [log in to unmask]
Subject: Urinary amylase
Dear Mailbase users,
We currently offer urinary amylase but a recent audit showed
that we are
receiving an average of just over one patient test a month,
plus
analysing some 5 times this number in EQA samples. However,
in addition
to serum amylase, we also have serum lipase as an additional
test for
pancreatitis, so are considering removing the urine test
from our
routine repertoire.
Have any users done this and, if so, have you encountered
any problems
from service users?
Regards,
Iain
Dr Iain Woodrow,
Clinical Biochemist
Department of Clinical Biochemistry
Pinderfields General Hospital
Aberford Rd
Wakefield
WF1 4DG
Phone 01924 317061 or 317000
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