Thank you for the answer Andreas.
I did suspect it was a rather ambiguous question.
In terms of doing whole-brain connectivity analysis, I've heard that something like 30 directions is minimum (when using the DTI data for research) and perhaps even 60 was the current recommended "standard". I guess I was hoping someone could substantiate this or refute this!?
Equally for B value above 1000?
Regarding the RESOLVE issues I'm afraid I don't know the specifics.