Nothing prescient about that. The MAD concept was first proposed by
Herzberg and Lau in 1967, much before sycnhrotrons were used for protein
Herzenberg, A. & Lau, H. S. M. (1967) Acta. Crystallogr. 22, 24-28.
The PNAS paper even refers to this article.
Le 13/03/13 16:46, Jacob Keller a écrit :
> Did anyone see this prescient line in the PNAS paper? Seems that the
> MAD concept was suggested way back then...
> "While the enhancement of anomalous scattering
> has not yet been examined in detail, it is in principle
> possible to use data collected at three wavelengths (15) to
> completely solve the phase problem. The synchrotron source
> is uniquely suited for these applications."