Hi Sheila
I have seen this thanks for sending. I have been looking at PPH for my PhD and the qualitative aspect has uncovered professionals concerns re increased rates of PPH potentially due to Syntocinon use. There was also an article which suggested the temporal rise could be due to this, although I can't lay my hands on it right now! (My endnote file is on a different computer!). Just wondered if anyone had contemporaneously evidence regarding this
Annette
Sent from my iPhone
On 24 Feb 2013, at 17:33, "Sheila Brown" <[log in to unmask]> wrote:
> Hi Annette,
> There is a systematic review which may be of interest by McDonald et
> al (2007). Here is the link. I just briefly looked at it. The authors
> conluded that there was no statistically significant difference
> between the two, with regards to blood loss, for blood loss over 1000
> mls.
> http://apps.who.int/rhl/reviews/langs/CD000201ru.pdf
> Sheila
>
> On 24 February 2013 17:24, Briley, Annette <[log in to unmask]> wrote:
>> Hi Laura
>> With using Syntocinon as first line what is your PPH rate? Anecdotally many
>> feel the temporal rise in PPH is due to oxytocin for AMTSL. Have you got
>> evidence this isn't the case?
>>
>> Annette
>>
>> Sent from my iPhone
>>
>> On 24 Feb 2013, at 16:56, "Laura Muir" <[log in to unmask]> wrote:
>>
>> Hello,
>>
>>
>>
>> In the last confidential enquiry it was recommended that women should not
>> receive syntometrine as a first line drug for the active management of the
>> third stage of labour due to the side effects not being able to be
>> predicted. There were 3 women who died of cerebral haemorrhage, one of whom
>> had normal blood pressure. One was known to have hypertension and the third
>> had laboured too rapidly for blood pressure recording.
>>
>>
>>
>> In my own unit, syntocinon only has been used for the active management of
>> the third stage for a number of years. As such there was a vast reduction in
>> the number of women who experienced vomiting and headache post birth which
>> interfered with the precious first moments of mother with baby.
>>
>>
>>
>> I think the question that should be asked is why are other units still using
>> syntometrine as a first line?
>>
>>
>>
>> Laura Muir
>>
>> Labour Suite Co-ordinator/ Supervisor of Midwives
>>
>> Ayrshire Maternity Unit
>>
>> Scotland
>>
>>
>>
>>
>>
>>
>>
>> ________________________________
>>
>> From: A forum for discussion on midwifery and reproductive health research.
>> [mailto:[log in to unmask]] On Behalf Of Martine Storey
>> Sent: 23 February 2013 15:26
>> To: [log in to unmask]
>> Subject: syntometrine induced eclamptic fits
>>
>>
>>
>> Hi midwives,
>>
>>
>>
>> We have recently had a case whereby a low risk woman had a grand mal fit
>> after being given syntometrine. She was treated with diazemuls and
>> phenytoin. All her PET associated blood films were normal, as was her blood
>> pressure. Her final diagnosis was eclamptic fit induced by syntometrine
>> administration. In her subsequent pregnancy she was not offered or given
>> this drug, getting syntocinon instead with no side effects.
>>
>>
>>
>> My query is how frequent is this phenomena and is there an increase in its
>> occurence? What are the factors that predispose to this happening?
>>
>>
>>
>> Martine Storey
>>
>> Labour Coordinator/Supervisor of Midwives
>>
>> QMC Campus, Nottingham
>
>
>
> --
> Sheila JS Brown
> 07840 296 731
>
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