On Mon, Jan 7, 2013 at 1:28 AM, Xiaopeng Hu <[log in to unmask]> wrote:
> We recently resolved an enzyme/inhibitor complex structure. The enzyme contains two NCS related active site and we did find extra density in both of them.However we observed that the two inhbitor moleculors are not NCS related, but partly overlaped if make a NCS moleculor. Has anyone else observed this before? Thanks for any help and suggestion!
If I'm not misunderstanding the question, some HIV protease inhibitor
complexes do this too. PDB ID 2fxe is a good example.
-Nat
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