AGENDA NOW AVAILABLE AND FINAL OPPORTUNITY TO REGISTER FOR THIS WORKSHOP
Design and Analysis of Trials in Rare Cancers
Joint Meeting of the Royal Statistical Society Medical Section and the MRC Hubs for Trials Methodology Research and the European Network for Cancer Research in Children and Adolescents and the International Rare Cancers Initiative
This meeting will bring together methodologists working in trials of rare cancers in the paediatric and adult setting, providing opportunity to share knowledge and discuss the advantages and disadvantages of different approaches and thereby identify areas requiring further research.
11:00 - 11:20 REGISTRATION AND COFFEE
Chair: Lucinda Billingham
11:20 - 11:30 Welcome, introduction and background - Lucinda Billingham
11:30 - 11:50 Efficient use of a scarce resource: the design concept for a trial in relapsed Ewing's sarcoma - Keith Wheatley
11:50 - 12:10 Two / three phase sampling designs and analyses - Norman Breslow
12:10 - 12:30 Two-phase sampling designs: an application to childhood leukemia - Maria Grazia Valsecchi
12:30 - 12:40 Discussion
12:40 - 13:40 LUNCH
Chair:-Maria Grazia Valsecchi
13:40 - 14:00 Taking the long view: how to design a series of phase III trials to maximise cumulative benefit - Marie-Cecile Le Deley
14:00 - 14:20 Using a selection design 'Pick the winner' in a COG phase II study of relapsed neuroblastoma - Wendy London
14:20 - 14:40 IRCI example in penile cancer using a Bayesian design - Lucinda Billingham
14:40 - 14:50 Discussion
14:50 - 15:10 TEA
Chair:-Keith Wheatley
15:10 - 15:30 Combining opinion with clinical data - John Whitehead
15:30 - 15:50 Multi-Arm Multi-Stage trials in rare diseases: an example in ocular melanoma - Matthew Sydes
15:50 - 16:10 Final discussion and identification of areas of further research
16:10-MEETING CLOSE
Venue: Royal Statistical Society Headquarters, 12 Errol Street, London, EC1Y 8LX (near the Barbican Centre)
Date: Friday October 5th 2012 - 11:00 to 16:10
There is no cost to attend the meeting but please register your intention to attend for catering purposes with Karen Biddle ([log in to unmask])
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