Dear Jay,
Your question does not have a generic answer as it depends on what
your experimental question is and what features you want to look at in
your EEG data. If for instance you want to study seizure onset you can
compare it to EEG recorded when there is no seizure (although it's
probably not completely normal but that depends on the patient). If
you want to look at some features in the EEG between seizures that are
still abnormal then you will need healthy controls. Perhaps it'd be a
good idea for you to work ask a trained neurologist to identify
'clean' EEG segments for you that you can use as control. I hope this
helps.
Best,
Vladimir
On Fri, Jul 27, 2012 at 8:51 AM, jay chen <[log in to unmask]> wrote:
> Dear Dr. Litvak:
>
> I only have EEG data from 10 epilepsy patients, but no EEG
> data from normal subjects. I was told that because the EEG signal
> before stimulus is like the signal from normal subjects, I can treat
> this period of EEG signal as control signal to compare with the
> epileptic EEG signal. I wonder this statement is correct? Or do you
> recommend to correct EEG data from normal subjects directly? Thanks
> for help.
>
>
> Best Regards
> Jay Chen
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