On Tue, Jun 12, 2012 at 8:53 PM, Frank von Delft
<[log in to unmask]> wrote:
> Finding 111 sites should be feasible without other tricks than very careful
> data collection (see below); if you have two or more copies in the ASU, you
> may find you need to do what the ribosome guys did, namely use other
> derivatives (e.g TaBr clusters) to locate your seleniums, and then phase.
With 40% of the complex having homologues in the PDB, you may be able
to place those subunits by MR, then use the phases from the incomplete
model to locate the seleniums.
-Nat
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