Dear FSL expert
I have a study aiming to assess the effect of caffeine on working memory
I have a 2back working memory task. In a repeated measures design, each subject performs 2 days (one with placebo, one with caffeine), and 2 2back tasks each day (total of 2x2 fMRI EPI BOLD runs per subject).
The problem is that caffeine has a direct vascular effect. To capture this, each subject additionally has an ASL on each day. The idea is to assess the global CBF changes in ASL, and to eliminate this effect from the fMRI EPI BOLD analysis.
I looked into the FEAT analysis, and there is in fact a perfusion analysis. Yet if I understood correctly, this analysis is rather intended for fMRI-like analysis of ASL instead of EPI data.
Are there any suggestions how I could use the ASL data to extract medication-related changes in CBF from the fMRI tasks??
Your help is highly appreciated
Sven
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