On 02/07/2012 08:31 AM, Dialing Pretty wrote:
> Dear All,
>
> After we refine the structure of the protein to satisfactory with
> satisfactory Rwork and Rfree, we pick water by phenix refine, and I find Rfree always increases slightly after the water picking refinment.
>
> Do you have nay idea to solve this problem or any comment?
>
> Cheers,
>
> Dialing
Well - it shouldnt!
Check if there is some problem..
Eleanor
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