Dear Chris
A whole series of studies from the early to late 90's did his for the growth hormone-GHR interaction.
Papers by Pearce, Cunningham, Clackson and Wells come to mind.
Also a recent study on the IL13-IL13R interaction by Lupardus et al has covered most of the interaction epitope.
Best regards
Savvas
On 07 Feb 2012, at 10:16, Chris Ulens <[log in to unmask]> wrote:
> Dear colleagues,
> I am looking for a few example studies in which a complete mutagenesis of all residue-ligand interactions has been conducted to evaluate the energetic contributions of each individual interaction.
> Thank you.
> Best regards.
> -Chris
>
> ---------------------------------------------------
> Chris Ulens, Ph.D.
> Lab of Structural Neurobiology
> Department of Cellular and Molecular Medicine
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