COURSE
Statistical analysis with missing data using multiple imputation and
inverse probability weighting
London School of Hygiene & Tropical Medicine
11th-13th June 2012
The course
Missing data frequently occur in both observational and experimental
research. They lead to a loss of statistical power, but more
importantly, may introduce bias into the analysis. In this course we
adopt a principled approach to handling missing data, in which the first
step is a careful consideration of suitable assumptions regarding the
missing data for a given study. Based on this, appropriate statistical
methods can be identified that are valid under the chosen assumptions.
The course will focus particularly on the practical use of multiple
imputation (MI) to handle missing data in realistic epidemiological and
clinical trial settings, but will also include an introduction to
inverse probability weighting methods and new developments which combine
these with MI.
Course organisers
Dr Jonathan Bartlett, Dr James Carpenter and Prof Mike Kenward
Who should apply?
Epidemiologists, biostatisticians and other health researchers with
strong quantitative skills and experience in statistical analysis. Stata
will be used for the computer practicals, and so familiarity with the
package is highly desirable, although full Stata code and solutions will
be provided.
Course content
The course will:
- provide an introduction to the issues raised by missing data, and the
associated statistical jargon (missing completely at random, missing at
random, missing not at random)
- illustrate the shortcomings of ad-hoc methods for 'handling' missing
data
- introduce multiple imputation for statistical analysis with missing
data
- compare and contrast this with other methods, in particular inverse
probability weighting and doubly robust methods, and
- introduce accessible methods for exploring the sensitivity of
inference to the missing at random assumption
Through computer practicals using Stata, participants will learn how to
apply the statistical methods introduced in the course to realistic
datasets.
Course fee
£600
To apply to attend this course, please go to
http://www.lshtm.ac.uk/study/cpd/statisticalanalysis.html
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