JiscMail Logo
Email discussion lists for the UK Education and Research communities

Help for SPORT-MED Archives


SPORT-MED Archives

SPORT-MED Archives


SPORT-MED@JISCMAIL.AC.UK


View:

Message:

[

First

|

Previous

|

Next

|

Last

]

By Topic:

[

First

|

Previous

|

Next

|

Last

]

By Author:

[

First

|

Previous

|

Next

|

Last

]

Font:

Proportional Font

LISTSERV Archives

LISTSERV Archives

SPORT-MED Home

SPORT-MED Home

SPORT-MED  January 2012

SPORT-MED January 2012

Options

Subscribe or Unsubscribe

Subscribe or Unsubscribe

Log In

Log In

Get Password

Get Password

Subject:

MEDICAL: TREATMENTS: Saw Palmetto no More Effective than Placebo for Urinary Symptoms

From:

"David P. Dillard" <[log in to unmask]>

Reply-To:

To support research in sports medicine <[log in to unmask]>

Date:

Sat, 28 Jan 2012 15:26:58 -0500

Content-Type:

TEXT/PLAIN

Parts/Attachments:

Parts/Attachments

TEXT/PLAIN (392 lines)

.

.

MEDICAL: TREATMENTS:

Saw Palmetto no More Effective than Placebo for Urinary Symptoms


.

.


Date: Tue, 27 Sep 2011 16:07:43 -0400
From: "NIH OLIB (NIH/OD)" <[log in to unmask]>
To: [log in to unmask]
Subject:  Saw Palmetto no More Effective than Placebo for Urinary Symptoms

.

.


U.S. Department of Health and Human Services

NATIONAL INSTITUTES OF HEALTH NIH News

National Institute of Diabetes and Digestive and Kidney Diseases

(NIDDK)

http://www.niddk.nih.gov/

.

.


Embargoed for Release: Tuesday, September 27, 2011, 4 p.m. EDT

.

.


CONTACT:

Bill Polglase

301-496-3583

e-mail:

[log in to unmask]

.

.


SAW PALMETTO NO MORE EFFECTIVE THAN PLACEBO FOR URINARY SYMPTOMS

.

.



NIH-funded study finds dietary supplement does not alleviate BPH

.

.


Saw palmetto, a widely used herbal dietary supplement, does not reduce 
urinary problems associated with prostate enlargement any better than a 
placebo, according to research funded by the National Institutes of 
Health. The study was published Sept. 28 in the Journal of the American 
Medical Association.


Prostate enlargement, also called benign prostatic hyperplasia (BPH), can 
cause frequent urination, a weak or intermittent urine stream and an 
inability to empty the bladder completely.  More than half of men in their 
60s, and up to 90 percent in their 70s and 80s, have symptoms of BPH.


The National Institute of Diabetes and Digestive and Kidney Diseases 
(NIDDK), the National Center for Complementary and Alternative Medicine 
(NCCAM) and the Office of Dietary Supplements (ODS) supported the study. 
All are part of the NIH.


According to Robert A. Star, M.D., director of the NIDDK's Division of 
Kidney, Urologic and Hematologic Diseases, the current study met an 
important need for rigorous evaluation of standard and higher doses of saw 
palmetto. The trial also confirmed results of the earlier NIDDK- and 
NCCAM-sponsored Saw Palmetto Trial for Enlarged Prostates (STEP), which 
found that a standard daily dose of 320 milligrams provided no greater 
symptom relief than placebo.


"Investigators designed the current trial to determine whether daily doses 
of up to 960 milligrams - three times the standard daily dose -- would 
prove better than a placebo at improving lower urinary tract symptoms in 
men due to BPH," said Star.  "We were disappointed to find that higher 
doses of saw palmetto did not improve symptoms more than placebo."


Josephine P. Briggs, M.D., director of NCCAM, added that this study 
further illustrates the importance of conducting research on botanical 
products that are used extensively by the general public.


"This was a well-designed study that addressed limitations of earlier, 
smaller trials - it was a multicenter study with a larger sample size and 
tested different doses of a carefully analyzed saw palmetto product," 
Briggs said.  "The NIH is committed to bringing rigorous science to the 
study of natural products and to building the evidence base that can guide 
consumer decisions."


The study was a double-blind randomized placebo-controlled clinical trial 
conducted at 11 North American clinical sites from June 2008 to October 
2010.  A cohort of 369 men aged 45 years or older participated, each with 
a peak urine flow rate of at least four milliliters per second at the 
beginning of the study -- which is less than normal.  Also, all had an 
American Urological Association Symptom Index (AUASI) score of between 
eight and 24 -- a lower score is better.  The AUASI score ranges from zero 
to 35.  Escalating doses of saw palmetto or placebo were given, starting 
at one, then two, and then three pills of 320 milligrams per day, with 
dose increases at 24 and 48 weeks.


The study measured the differences between the AUASI score at the start of 
the trial and after 72 weeks of treatment.  Secondary measures included 
improvements in frequency, nocturia (nighttime urination), peak urine 
flow, prostate-specific antigen (PSA) level, sexual function, incontinence 
and sleep quality.


Between baseline and 72 weeks, mean AUASI scores decreased from 14.4 to 
12.2 points with saw palmetto extract and from 14.7 to 11.7 points with 
placebo.  The group average change in AUASI score from baseline to 72 
weeks between the saw palmetto and placebo groups was 0.79 points, 
favoring placebo. Saw palmetto was not more effective than placebo in 
reducing urinary symptoms for any of the secondary outcomes.


According to Joseph M. Betz, Ph.D., director of the Analytical Methods and 
Reference Materials program at ODS and a study co-author, the study used a 
very well-characterized saw palmetto product.  Through batch testing, 
study investigators took extreme care to ensure that the composition of 
the supplement was consistent over the whole study.


"Saw palmetto and other herbs are often manufactured in different ways, so 
no two brands are likely to have the same composition," Betz said.


Rottapharm/Madaus, Cologne, Germany, donated the saw palmetto extract and 
matching placebo used in the study.

.


For more information on the trial, search for NCT00603304 at

.

http://www.clinicaltrials.gov

.

Learn about BPH at

.

http://kidney.niddk.nih.gov/kudiseases/pubs/prostateenlargement

.

To interview an NIH official or scientist, contact:

.

Bill Polglase

NIDDK

301-435-8115

or

301-496-3583

(BPH and urinary symptoms)

.

NCCAM Press

NCCAM

301-496-7790

(complementary and alternative medicine)

.

Kelli Marciel

ODS

301-496-4819

(dietary supplements)

.

.


The NIDDK, a component of the NIH, conducts and supports research on 
diabetes and other endocrine and metabolic diseases; digestive diseases, 
nutrition and obesity; and kidney, urologic and hematologic diseases. 
Spanning the full spectrum of medicine and afflicting people of all ages 
and ethnic groups, these diseases encompass some of the most common, 
severe and disabling conditions affecting Americans. For more information 
about the NIDDK and its programs, see

.

http://www.niddk.nih.gov

.

The NCCAM's mission is to define, through rigorous scientific 
investigation, the usefulness and safety of complementary and alternative 
medicine (CAM) interventions and their roles in improving health and 
health care. For additional information, call NCCAM's Clearinghouse toll 
free at

1-888-644-6226

or visit the NCCAM Web site at

.

http://nccam.nih.gov

.

The mission of the NIH ODS is to strengthen knowledge and understanding of 
dietary supplements by evaluating scientific information, stimulating and 
supporting research, disseminating research results, and educating the 
public to foster an enhanced quality of life and health for the U.S. 
population. For additional information about ODS, visit

.

http://ods.od.nih.gov

.

About the National Institutes of Health (NIH): NIH, the nation's medical 
research agency, includes 27 Institutes and Centers and is a component of 
the U.S. Department of Health and Human Services. NIH is the primary 
federal agency conducting and supporting basic, clinical, and 
translational medical research, and is investigating the causes, 
treatments, and cures for both common and rare diseases. For more 
information about NIH and its programs, visit

.

http://www.nih.gov

.

.

.


##

.

.

.


This NIH News Release is available online at:

http://www.nih.gov/news/health/sep2011/niddk-27.htm

.

.

.




Sincerely,
David Dillard
Temple University
(215) 204 - 4584
[log in to unmask]
http://daviddillard.businesscard2.com
Net-Gold
http://groups.yahoo.com/group/net-gold
Index: http://tinyurl.com/myxb4w
http://listserv.temple.edu/archives/net-gold.html
http://groups.google.com/group/net-gold?hl=en
General Internet & Print Resources
http://guides.temple.edu/general-internet
COUNTRIES
http://guides.temple.edu/general-country-info
EMPLOYMENT
http://guides.temple.edu/EMPLOYMENT
TOURISM
http://guides.temple.edu/tourism
DISABILITIES
http://guides.temple.edu/DISABILITIES
INDOOR GARDENING
http://tech.groups.yahoo.com/group/IndoorGardeningUrban/
Educator-Gold
http://groups.yahoo.com/group/Educator-Gold/
K12ADMINLIFE
http://groups.yahoo.com/group/K12AdminLIFE/
THE COLLEGE LEARNING CENTER
http://tinyurl.com/yae7w79
Nina Dillard's Photographs on Net-Gold
http://tinyurl.com/36qd2o
and also http://gallery.me.com/neemers1
http://www.flickr.com/photos/neemers/
Net-Gold Membership Required to View Photos
Twitter: davidpdillard



Bushell, R. & Sheldon, P. (eds),
Wellness and Tourism: Mind, Body, Spirit,
Place, New York: Cognizant Communication Books.
Wellness Tourism: Bibliographic and Webliographic Essay
David P. Dillard
http://tinyurl.com/p63whl
http://tinyurl.com/ou53aw



INDOOR GARDENING
Improve Your Chances for Indoor Gardening Success
http://tech.groups.yahoo.com/group/IndoorGardeningUrban/
http://groups.google.com/group/indoor-gardening-and-urban-gardening



SPORT-MED
https://www.jiscmail.ac.uk/lists/sport-med.html
http://groups.google.com/group/sport-med
http://groups.yahoo.com/group/sports-med/
http://listserv.temple.edu/archives/sport-med.html



HEALTH DIET FITNESS RECREATION SPORTS TOURISM
http://health.groups.yahoo.com/group/healthrecsport/
http://groups.google.com/group/healthrecsport
http://healthrecsport.jiglu.com/
http://listserv.temple.edu/archives/health-recreation-sports-tourism.html

.

.

Please Ignore All Links to JIGLU
in search results for Net-Gold and related lists.
The Net-Gold relationship with JIGLU has
been terminated by JIGLU and these are dead links.
http://groups.yahoo.com/group/Net-Gold/message/30664
http://health.groups.yahoo.com/group/healthrecsport/message/145

.

.

Top of Message | Previous Page | Permalink

JiscMail Tools


RSS Feeds and Sharing


Advanced Options


Archives

March 2020
February 2020
December 2019
September 2019
July 2019
June 2019
April 2019
February 2019
January 2019
December 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013
October 2013
September 2013
August 2013
July 2013
June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
December 2008
October 2008
September 2008
May 2008
February 2008
November 2007
October 2007
August 2007
June 2007
May 2007
March 2007
January 2007
December 2006
November 2006
September 2006
August 2006
July 2006
June 2006
May 2006
April 2006
March 2006
February 2006
January 2006
December 2005
November 2005
October 2005
September 2005
July 2005
June 2005
May 2005
April 2005
March 2005
February 2005
December 2004
November 2004
October 2004
September 2004
August 2004
July 2004
June 2004
April 2004
March 2004
February 2004
January 2004
December 2003
November 2003
October 2003
September 2003
August 2003
July 2003
June 2003
May 2003
April 2003
March 2003
February 2003
January 2003
December 2002
November 2002
October 2002
August 2002
July 2002
June 2002
April 2002
March 2002
February 2002
November 2001
October 2001
September 2001
August 2001
July 2001
June 2001
May 2001
April 2001
February 2001
January 2001
December 2000
November 2000
October 2000
September 2000
August 2000
July 2000
June 2000
May 2000
April 2000
March 2000
February 2000
January 2000
December 1999
November 1999
October 1999
September 1999
August 1999
July 1999
June 1999
May 1999
April 1999
March 1999
February 1999
January 1999
December 1998
November 1998
October 1998
September 1998


JiscMail is a Jisc service.

View our service policies at https://www.jiscmail.ac.uk/policyandsecurity/ and Jisc's privacy policy at https://www.jisc.ac.uk/website/privacy-notice

Secured by F-Secure Anti-Virus CataList Email List Search Powered by the LISTSERV Email List Manager