Hi Stephen,
you are right. I am a bit confused on how to go on with my exploration of
frontostriatal functional connectivity.
I have found that the a polymorphism have an effect in the same direction
on both a seed in the medial frontal cortex and a seed in the ventral
striatum. I would like to explore the strength of the functional
connectivity between these two seeds in the different polymorphisms. Have
you any suggestion on how to explore this? I have few experience in
seed-based analysis, so I apologize if my question is trivial
Thank you
Angela
> Hi - it's not very clear to me what you're asking - are you saying that
> you want to estimate the *spatial* correlation between two maps, created
> from two different seeds?
>
> This isn't really a very standard thing to do…..?
>
> Cheers.
>
>
>
> On 7 Nov 2011, at 08:56, Angela Favaro wrote:
>
>> Dear FSL experts,
>> I have the z-transformed maps of RSFC for two seeds (for any subjects)
>> and
>> I would like to test the correlation between the two using randomise,
>> including the correlation per group interaction (cases vs controls).
>>
>> How can I do this?
>>
>> Is it right to use the maps of the first seed as the input file and the
>> maps of the second seed as an EV?
>> To test for interaction, perhaps I have to build two merged files of
>> maps
>> (one with 0s in controls and the other with 0s in cases) and demeaned
>> across groups. Is it right?
>> Do I have to use the -d demean option in randomise, too?
>>
>> Thank you for any help
>>
>> Best,
>>
>> Angela
>>
>
>
> ---------------------------------------------------------------------------
> Stephen M. Smith, Professor of Biomedical Engineering
> Associate Director, Oxford University FMRIB Centre
>
> FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK
> +44 (0) 1865 222726 (fax 222717)
> [log in to unmask] http://www.fmrib.ox.ac.uk/~steve
> ---------------------------------------------------------------------------
>
>
>
>
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