Hi Gabor,
Have a look at the following paper
http://www.ncbi.nlm.nih.gov/pubmed/11323803
The effect of applying the DTI model to different partial volume patterns is explored. For crossing fibres, you basically expect some reduction in the estimated MD, compared to the ground truth. But the effect is not as big as in the FA.
Cheers,
Stam
On 24 Oct 2011, at 11:25, Gabor Perlaki wrote:
> Hi all,
>
> Does anybody know whether the dtifit program can accurately measure the mean diffusivity (MD) in regions with crossing fibers? I know that FA values are not too accurate in these regions (using conventional DTI), but maybe the MD is left affected by the validity of the gaussian model. Does anybody know some articles about this issue, or a comparative article which compares DTI-based MD and MD calculated by more sophisticated methods (Q-ball, DSI, HARDI,...)?
>
>
> Thanks a lot,
> Gábor
>
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