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Subject:
Re: is codon optimization worth it?
From:
Dima Klenchin <[log in to unmask]>
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Date:
Fri, 30 Sep 2011 11:48:42 -0500
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text/plain
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text/plain (8 lines)
>In theory, if the rare codons are all covered by Rosetta's extra >tRNAs, codon optimization should not make any difference. In practice it does because frequently it's not codon optimization per se but changing local mRNA structure. - Dima
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