For our block design we used SPM8 to create a contrast map that would show brain activation. However, when we examined the the significantly activated regions in MarsBar we had a negative percent signal change. We are not sure why we are getting two different results in SPM and Marsbar. Also, we are unsure of the interpretation, does the negative percent signal change in MarsBar mean deactivation? Any comments would be appreciated, thanks for the help in advance.