we have conducted a long-term study in depressive patients using an emotional face paradigm (4 conditions: happy, neutral, fearful, disgusted faces). Patients were scanned on two timepoints (pre- and post-treatment); additionally a group of controls was scanned twice.
Now I wonder which second level analysis to perform:
a) A flexible factorial design for repeated measures with the factors timepoint (pre- vs. post-treatment) & group (patients vs. controls)
b) Separate t-tests for:
1) patients vs. controls pre-treatment (2-sample t-test)
2) patients vs. controls post-treatment (2-sample t-test)
3.) patients pre-treatment vs. patients post-treatment (paired t-test)
Thanks in advance & best regards,