Also more importantly--- getting an infusion is generally a fairly
anxiogenic experience--- I guess it of course depends on how the drug
is infused... but at least when I've seen PET injections done in the
past people's heart rates generally shoot up during the infusion...
even for non-PET injections (i.e. radiation = scary)... since many
infusion pumps don't heat the solution prior to infusion, it's quite
possible to "feel" the relatively cold solution being injected into
your arm... again not exactly a baseline condition.
dg
On Mon, May 23, 2011 at 4:13 PM, Matt Glasser <[log in to unmask]> wrote:
> I am not sure if there is any literature out there on the resting state
> networks of donkeys (or humans) during drug infusions vs afterwards. I
> would think that assuming that as soon as an infusion is completed the brain
> instantly changes to a new state isn't right and more likely the change is
> gradual from how the brain is before the infusion to how it is after.
> Therefore you might not want to treat that data as either pre-drug or
> post-drug.
>
> Peace,
>
> Matt.
>
> -----Original Message-----
> From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf
> Of Claudia Huerta
> Sent: Monday, May 23, 2011 2:58 PM
> To: [log in to unmask]
> Subject: [FSL] Resting state and drug infusion
>
> Hi,
>
> I'm trying to asses the changes on resting state networks after a drug
> infusion. The drug infusion last around 10 minutes.
> Is it OK to treat the data during the infusion as Resting state data?
> Thanks
>
> Ivette
>
>
--
David A Gutman, M.D. Ph.D.
Center for Comprehensive Informatics
Emory University School of Medicine
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