Reply-To: | | [log in to unmask][log in to unmask]> wrote: >>> Hi Donald, >>> Thanks for your response. When you say "you don't want >>> to filter out anything related to neural activity", I'm presuming that you >>> are referring to the deconvolved neural signal? >>> >>> If so, that makes sense. However, X0 also contains user-specified nuisance >>> covariates. I would have thought it would make sense to remove those, >>> depending on what they were (e.g., movement parameters)? I guess they can >>> always be entered into the PPI regression model... >>> >>> >>> On 05/05/2011 11:57, "MCLAREN, Donald" <[log in to unmask]> wrote: >>> >>>> I could be wrong, Karl or Darren please correct me if I am. >>>> >>>> X0 is composed of the high-pass filter and constant term. Thus, you >>>> want to filter these out of the Yc regressor. However, you don't want >>>> to filter out anything related to neural activity, so you wouldn't >>>> want to filter your signal and then predict the neural activity from >>>> the filtered signal, especially filtering frequencies. >>>> >>>> Best Regards, Donald McLaren >>>> ================= >>>> D.G. McLaren, Ph.D. >>>> Postdoctoral Research Fellow, GRECC, Bedford VA >>>> Research Fellow, Department of Neurology, Massachusetts General >>>> Hospital and Harvard Medical School >>>> Office: (773) 406-2464 >>>> ===================== >>>> This e-mail contains CONFIDENTIAL INFORMATION which may contain >>>> PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED >>>> and which is intended only for the use of the individual or entity >>>> named above. If the reader of the e-mail is not the intended recipient >>>> or the employee or agent responsible for delivering it t6B[e |