Dear Jacob,
I do not have exactly what you are asking about but some clues.
I am not fond of using buried surface area as an indicator of anything in particular and always use energy estimates, however unreliable they may be. In J.Comp.Chem. 31(1),133-143, I put a probability plot for PISA to give erroneous oligomeric states as a function of complex's free energy (page 141, long-dashed line). In page 138, there's a plot showing correlation between free energy (as estimated by PISA) and buried surface energy. Combining the two, you may get a rough answer to your question :)
Hope this helps,
Eugene.
On 26 May 2011, at 03:41, Jacob Keller wrote:
> Dear Crystallographers,
>
> is anyone aware of a reference or plot addressing buried surface area
> (or PISA output values) versus veracity of a complex? I am trying to
> determine the physiological relevance of a
> crystallographically-observed assembly, and would love to put my PISA
> output in the context of verified complexes versus crystal contacts.
>
> Thanks,
>
> Jacob
>
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> Jacob Pearson Keller
> Northwestern University
> Medical Scientist Training Program
> cel: 773.608.9185
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