Hi,
Yes - we feel that doing the first level analysis in the functional space
reduces the amount of computation, keeps the results closer to the
acquired data (isolating them from registration errors) and given
typical resolution and smoothing that it done, has no drawback with
respect to spatial accuracy.
All the best,
Mark
On 18 Mar 2011, at 23:55, Magno R. Guillen B. wrote:
> Thank you for the explanation.
>
> So doing the registration before the first level analysis just would add burden to the system and does not provide further spatial accuracy to the statistical analysis result.
>
>
>
>
>
> On Fri, Mar 18, 2011 at 7:07 PM, Mark Jenkinson <[log in to unmask]> wrote:
> Hi,
>
> The activations at the first level are calculated directly from the functional
> images without any registration (although there is motion correction).
>
> Registration is done separately, with the functional images registered
> to the anatomical/structural images, and then these are registered to
> standard space. Then the first level results are transformed into standard
> space when a higher level analysis is initiated.
>
> I hope this answers your question.
> All the best,
> Mark
>
>
>
> On 18 Mar 2011, at 20:03, Magno Guillen wrote:
>
> > Hi FSL EXpert,
> >
> > I would appreciate if somebody clarify to me the way that the coregistration between the High and Low res anatomical and the activation map is performed.
> >
> > Intuitively I think that the activation map is calculated and the result is coregistered with the low resolution and then the high resolution anatomical, is that Right? There is also a more time consuming event, which is to coregister each time point of the 4D file to the anatomical MR.
> >
> > Any body knows the actual implementation of Anatomical MR and fmri results?
> >
> > Thanks
> >
>
>
>
> --
> Magno R. Guillen, PhD
> Office: 2220 ECE Building
> Phone: (305) 348 - 4106
> College of Engineering
> Center of Advanced Education & Technology - CATE
> Florida International University - FIU
> URL--> http://web.eng.fiu.edu/~mguil004/
>
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