not sure whether this option has been mentioned before ...
i think what we really would like to do is decide by the quality of the
density. i see that this is difficult.
so, short of that ... how about the figure of merit in refinement ?
wouldn't the fom reflect how useful our data really are ?
ingo
On 03/03/2011 12:29, Roberto Battistutta wrote:
> Dear all,
> I got a reviewer comment that indicate the "need to refine the structures at an appropriate resolution (I/sigmaI of >3.0), and re-submit the revised coordinate files to the PDB for validation.". In the manuscript I present some crystal structures determined by molecular replacement using the same protein in a different space group as search model. Does anyone know the origin or the theoretical basis of this "I/sigmaI >3.0" rule for an appropriate resolution?
> Thanks,
> Bye,
> Roberto.
>
>
> Roberto Battistutta
> Associate Professor
> Department of Chemistry
> University of Padua
> via Marzolo 1, 35131 Padova - ITALY
> tel. +39.049.8275265/67
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> VIMM (Venetian Institute of Molecular Medicine)
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>
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