Despite advances in understanding aspects of the etiology of some developmental neuropsychiatric disorders, translating these insights into clinical practice has remained daunting. Significant obstacles include the lack of reliable and valid biomarkers and an insufficient understanding of the underlying pathophysiology. We believe that a community-wide effort focused on advancing functional and structural imaging examinations of the developing brain will accelerate the rate at which neuroscience can inform clinical practice.
To recruit the global scientific community to address childhood psychiatric illness, we are pleased to announce the 'ADHD-200 Global Competition.' Investigators across all disciplines and at all levels of training are invited to participate in a competition to identify:
1) The Highest Performance Imaging-Based Diagnostic Classification Algorithm for ADHD. Participants will develop and train a diagnostic classifier (ADHD-Combined type, ADHD-Inattentive type, typically developing control) based on the ADHD-200 datasets (http://fcon_1000.projects.nitrc.org/indi/adhd200/index.html) that contain structural and resting-state fMRI datasets for 285 individuals diagnosed with ADHD and 491 typically developing individuals. On July 1, 2010 a test set comprised of previously unreleased datasets will be distributed via NITRC, without diagnostic labels. Participants will be asked to submit their diagnostic classifications for the unlabeled datasets by August 15th, 2010, along with a brief report outlining their analytic approach. The winning entry will be chosen based upon prediction accuracy. Note: The test set will include unreleased datasets from sites included in the ADHD-200 release, as well as additional sites whose data were not included in the release.
2) The Most Innovative Neuroscientific Examination of ADHD. Participants are invited to use the ADHD-200 datasets released on March 1st to address the pathophysiology of ADHD, and to submit a novel manuscript reporting their findings by August 1, 2010. Each entry will be independently scored by five 'blind' judges based upon innovation, potential impact, and elegance of analytic approach. A single winning entry will be selected based upon their composite score.
Eligibility: Individuals from all disciplines and training levels are invited to participate. Team-based and single-person entries are allowed. For team-based entries, a team representative should be specified for the purpose of communications and travel to Washington D.C. if selected as the winning entry. Individuals or teams interested in participating should notify Michael Milham of their intent by July 1, 2010 ([log in to unmask]); entry submission directions will be provided at that time.
Award: ADHD-200 global competition winners will be invited to attend the National Institute on Drug Abuse (NIDA) pre-conference symposium preceding the Society for Neuroscience Annual Meeting in Washington D.C., where they will be publicly recognized for their accomplishment and given the opportunity to present their work. Travel costs for a representative from each winning entry will be covered courtesy of NIDA.
Award Notification Date: September 1, 2010
Michael P. Milham, MD, PhD
Nathan S. Kline Institute for Psychiatric Research
Leon Levy Assistant Professor of Child and Adolescent Psychiatry
NYU Langone Medical Center
Associate Director, Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center