JiscMail Logo
Email discussion lists for the UK Education and Research communities

Help for SPM Archives


SPM Archives

SPM Archives


SPM@JISCMAIL.AC.UK


View:

Message:

[

First

|

Previous

|

Next

|

Last

]

By Topic:

[

First

|

Previous

|

Next

|

Last

]

By Author:

[

First

|

Previous

|

Next

|

Last

]

Font:

Proportional Font

LISTSERV Archives

LISTSERV Archives

SPM Home

SPM Home

SPM  February 2011

SPM February 2011

Options

Subscribe or Unsubscribe

Subscribe or Unsubscribe

Log In

Log In

Get Password

Get Password

Subject:

Re: DCM: mutual interactions between networks

From:

Darren Gitelman <[log in to unmask]>

Reply-To:

Darren Gitelman <[log in to unmask]>

Date:

Thu, 10 Feb 2011 11:05:48 -0600

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (83 lines)

Marco



On Thu, Feb 10, 2011 at 5:07 AM, marco tettamanti
<[log in to unmask]> wrote:
> Dear all,
> I don't think that this question has been addressed before:
>
> I would like to set up a DCM analysis with fMRI data to investigate the
> following issue: we have identified an activation in a very well known
> network of 4 brain regions (A,B,C,D), and we believe that, in our task, this
> network can be gated - depending on which one of 2 different input
> modalities is involved - by the activity of two other distinct networks,
> each including 3 brain regions (E,F,G, or H,I,J).
> That is, we would like to assess how network EFG interacts with network ABCD
> in modality 1 and how network HIJ interacts with network ABDC in modality 2,
> in the context of a sort of 2x2 (Modality x network-network interaction)
> factorial design.
>
> I presume that one could address this, by simply treating each brain region
> independently, and for instance by using BMS to test whether the preferred
> model fits the expected interaction patterns, but I think that there may be
> problems with the relatively large number of regions (>8).

You can deal with this by setting up the DCM file from the command
line. If you set up a simpler DCM using the GUI you will see what
fields you need. The 8 region limitation is mostly due to the gui (and
memory).

> I also presume that the question could be approached by non-linear DCM, even
> though I think that non-linear DCM has been only used in the context of the
> influence of one single region on a system of interconnected regions, and
> not in the context of network-network interactions.

I'm not sure how you could use a non-linear DCM in this scenario. You
can't really setup a small DCM network as an input, per se. The two
"subnetworks" would just be connected into the larger 4 region network
perhaps through a common area. This would be through an intrinsic
connection. DCM only accepts as inputs the condition-type vectors that
it extracts from an SPM.mat file. You would also need other actual
inputs into each of the subnetworks in order to drive overall system
activity. Non-linear DCM's can be used to modulate an intrinsic
connection, so perhaps you are thinking of using the 3 region
subnetworks to modulate an external input into the 4 region network?
However, I don't think you can modulate an input as DCM is currently
set up, and you would still need to drive the subnetworks in some way.

Darren

>
> Can anyone suggest a more direct way to approach this issue?
>
> Thank you and all the best,
> Marco
>
> --
> Marco Tettamanti, Ph.D.
> San Raffaele Scientific Institute
> Via Olgettina 58
> I-20132 Milano, Italy
> Tel. ++39-02-26434888
> Fax ++39-02-26434892
> Email: [log in to unmask]
>
> -----------------------------------------------------------------------------------
> SOSTIENI ANCHE TU LA RICERCA DEL SAN RAFFAELE.
> NON C'E' CURA SENZA RICERCA.
> Per donazioni: ccp 42437681 intestato a Fondazione Arete' Onlus del San
> Raffaele.
> Per informazioni: tel. 02.2643.4461 - www.sanraffaele.org
>



-- 
Darren Gitelman, MD
Northwestern University
710 N. Lake Shore Dr., 1122
Chicago, IL 60611
Ph: (312) 908-8614
Fax: (312) 908-5073

Top of Message | Previous Page | Permalink

JiscMail Tools


RSS Feeds and Sharing


Advanced Options


Archives

October 2019
September 2019
August 2019
July 2019
June 2019
May 2019
April 2019
March 2019
February 2019
January 2019
December 2018
November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013
October 2013
September 2013
August 2013
July 2013
June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
2006
2005
2004
2003
2002
2001
2000
1999
1998


JiscMail is a Jisc service.

View our service policies at https://www.jiscmail.ac.uk/policyandsecurity/ and Jisc's privacy policy at https://www.jisc.ac.uk/website/privacy-notice

Secured by F-Secure Anti-Virus CataList Email List Search Powered by the LISTSERV Email List Manager