I have used FAST to segment T1 weighted MPRAGE images into three classes. (Skull stripping and other image preparation has been done as used in SIENAX.) White matter regions which are very bright in FLAIR images tend to be darker in the T1 than other white matter. As a result FAST tends to misclassify this white matter as gray matter. Do you have any suggestions for automatically identifying FLAIR hyperintensities in the white matter that are misclassified as gray matter by FAST? I have MPRAGE, FLAIR and T2 images of my subjects.
Thanks for your help,
Keith
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