Hello John,
we are aiming at quantifying the coregistration quality of 2 normalisation
"pipelines" for animal (mouse) scans.
(basically differing be the way a template is generated).
Basically, the idea was to assess the similarity of the resulting
(spatially normalised) scans by
normalising all of them on eachother (all possible permutations) and sum up
a measure of the deformation
over all permutations. This could theoretically allow to state that
pipeline A or B leads to better alignment.
What would be a simple measure to quantify the overall deformation between
a scan S1 and S2?
For now, we produced the deformation fields based on S1_sn.mat (gained via
the normalisation function),
and intended to sum up the values over e. g. a brain mask. We then ran into
the practical problem of
finding that the deformation field image comprises only one, not three images.
Thanks in advance for any advice on this problem,
Philipp
Max Planck Institute of Psychiatry
NMR Research Group
Kraepelinstr. 2-10
80804 Munich
Mail: [log in to unmask]
Phone: 0049-89-30622-413
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