Dear zq deng,
The standard method, I dare say, in such a case is micro seeding:
reduce the precipitant to a concentration so that you just do not get crystals
any more, wait until the drop equilibrates (about one day in the case your
precipitant is a salt, up to 5-7 days for high MW PEGs),
then use a cat's whisker for micro seeding into that drop.
Well, that's micro seeding in a nut shell.
Tim
On Thu, May 06, 2010 at 04:03:46PM +0800, zq deng wrote:
> hello,everybody . due to excess nucleation,I often get many tiny crystals
> instead of few,large crystals.i wana optimize the condition, does anyone
> have adivce about this?
>
> Best regards.
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Tim Gruene
Institut fuer anorganische Chemie
Tammannstr. 4
D-37077 Goettingen
GPG Key ID = A46BEE1A
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