Protein Production Core in the Enzyme Function Initiative
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We are looking to recruit individuals with extensive experience in
molecular biology, protein purification, crystallization and automation to
join the Protein Production Core of the newly established NIH-funded
Enzyme Function Initiative (EFI). The goal of the EFI is to develop a
general sequence/structure-based strategy for facilitating the discovery
of in vitro enzymatic activities and in vivo physiological functions of
uncharacterized enzymes discovered in genome projects. This goal will be
accomplished by integrating informatics, structural biology and
computational chemistry with enzymology, genetics and metabolomics. The
EFI involves 13 investigators at 8 academic institutions.
The Protein Production Core is located within the Macromolecular
Therapeutics Development Facility at the Albert Einstein College Medicine
and is fully equipped to pursue all aspects of state-of-the-art structural
genomics. The Protein Production Core exploits extensive automation and an
active program focused on the development of novel protein
expression/purification strategies, utilizing both prokaryotic and
eukaryotic hosts.
Interested candidates should provide a CV and arrange for two letters of
support to be forwarded to Dr. Ron Seidel at [log in to unmask]
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