Hi Stephen,
Thank you for your response.
I need to know more about the efficiency. We know that it is very hard to get
good efficiency about fMRI design if you have multiple events in one trial,
however we have to do that for we study conditioned response, which means
we need to include one signal and one stimulus for each trial. Another problem
is the SNR of the amygdala that we are interetsed is bad compared with other
brain areas, so we must improve the efficiency otherwise we can not get
significant results. I learned that one way to solve this problem is to increase
the variance of the baseline, and I am trying to do that. In some similar stuies
I found they put a 30s longer baseline at the start of each run, so I am
wondering if this is a good method to improve the design efficiency for my
study. Could you please give me some suggestion about how to improve
design efficiency about this issue(I have 2 runs)?
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