Some of you might be curious about the "Ajees et al debacle" that Jacob mentioned in his message. Here are two links:
Nature Brief Communication that questioned the validity of one of Murthy's structures:
http://www.nature.com/nature/journal/v448/n7154/full/nature06102.html
Murthy's rebuttal:
http://www.nature.com/nature/journal/v448/n7154/full/nature06103.html
Jack
--
John J. Tanner
Professor of Chemistry and Biochemistry
University of Missouri-Columbia
125 Chemistry Building
Columbia, MO 65211
Phone: 573-884-1280
Fax: 573-882-2754
Email: [log in to unmask]
http://www.chem.missouri.edu/TannerGroup/tanner.html
________________________________
From: Jacob Keller <[log in to unmask]>
Reply-To: Jacob Keller <[log in to unmask]>
Date: Thu, 10 Dec 2009 11:59:49 -0600
To: <[log in to unmask]>
Conversation: [ccp4bb] FW: pdb-l: Retraction of 12 Structures
Subject: Re: [ccp4bb] FW: pdb-l: Retraction of 12 Structures
I assume this is the denouement of the Ajees et al debacle a while back?
Does this mean all authors on all of those papers were complicit? Otherwise,
how would one author alone perpetrate this kind of thing? He pretends to go
to the synchrotron, comes back with the hkl file, and goes from there? What
about the crystals? Grows some lysozyme crystals, labels as protein x,
proceeds to go "to the synchrotron" and then...? This whole thing is really
hard to imagine--is there an "initiation" procedure in that lab, when the
"noble lie" is revealed to all would-be authors?
Jacob Keller
*******************************************
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
Dallos Laboratory
F. Searle 1-240
2240 Campus Drive
Evanston IL 60208
lab: 847.491.2438
cel: 773.608.9185
email: [log in to unmask]
*******************************************
----- Original Message -----
From: "Ibrahim Moustafa" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Thursday, December 10, 2009 8:16 AM
Subject: [ccp4bb] FW: pdb-l: Retraction of 12 Structures
> Hi all,
>
> I want to share the following e-mail received from pdb-l.
>
> It is sad to see something like that!
>
> regards,
> Ibrahim
>
>
> ------ Forwarded Message
> From: Michael Sadowski <[log in to unmask]>
> Date: Thu, 10 Dec 2009 04:22:28 -0800 (PST)
> To: <[log in to unmask]>
> Subject: pdb-l: Retraction of 12 Structures
>
> Dear All,
>
> Better check your data!
>
> Apologies to those who have seen this.
>
> S.
>
> -----
>
> "The University of Alabama at Birmingham has issued a statement indicating
> that a former UAB researcher may have fabricated or falsified data about
> protein structures that are contained in the Protein Data Bank.
>
> The university did not include a name of the researcher, but the
> Birmingham
> News this week reported that the scientist is H.M. Krishna Murthy and an
> independent review by BioInform of the PDB shows that Murthy is associated
> with all of the proteins that UAB said were falsified.
>
> The newspaper said that a probe of Murthy's research has been underway
> since
> 2007.
>
> "After a thorough examination of the available data, which included a
> re-analysis of each structure alleged to have been fabricated, the
> committee
> found a preponderance of evidence that structures 1BEF, 1CMW, 1DF9/2QID,
> 1G40, 1G44, 1L6L, 2OU1, 1RID, 1Y8E, 2A01, and 2HR0 were more likely than
> not
> falsified and/or fabricated and recommended that they be removed from the
> public record," the university said in its statement this week."
>
> -----
> http://www.genomeweb.com/informatics/university-alabama-says-researcher-fabr
> icated-protein-structures-now-protein-dat?utm_source=feedburner&utm_medium=f
> eed&utm_campaign=Feed%3A+genomeweb%2Fbioinform+%28BioInform%29
>
>
> http://main.uab.edu/Sites/reporter/articles/71570/
>
> http://blog.al.com/birmingham-news-stories/2009/12/ex-uab_researchers_work_m
> ay_be.html
>
>
>
>
> TO UNSUBSCRIBE OR CHANGE YOUR SUBSCRIPTION OPTIONS, please see
> https://lists.sdsc.edu/mailman/listinfo.cgi/pdb-l .
>
>
> ------ End of Forwarded Message
>
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