PhD Projects for October 2010
Three and four year programmes on offer
The MRC Centre for Neuropsychiatric Genetics and Genomics at Cardiff University School of Medicine is recruiting for both 3 and 4 year PhD programmes. We currently have 23 registered PhD students and have an excellent track record of successful postgraduate researchers.
The Centre's research is organised around the following major themes:
- Psychosis and Major Affective Disorders - schizophrenia, mood disorder;
- Neurodegenerative Disorders - Alzheimer's disease, Huntington's disease, PSP, Parkinson's Disease, neuromuscular disorders;
- Developmental Disorders - dyslexia, ADHD, childhood depression, pre-natal environmental influences on behaviour and Mouse Behavioural Genetics - X chromosome genes and behaviour, sexually dimorphic behaviours and behavioural epigenetics.
Research in all these areas is underpinned by the Bioinformatics Biostatistics Unit and by work on functional genomics.
The four year programme includes a first year with an intensive tutorial-based three month introduction followed by research laboratory rotations. In years 2-4 students undertake a single research project of their choice.
The three year programme offers a series of PhD projects from Centre supervisors: these are available at http://www.cf.ac.uk/medic/irg-neur/phdprojects/index.html.
Application procedure
Prospective students should have a first degree with at least a 2.1 or higher academic qualifications in a subject appropriate to the project they wish to undertake. Applications should be made to [log in to unmask] with a CV including the names of two academic referees and a covering letter indicating which programme or projects they are interested in and why by 31st January 2010.
For further information:
Ms Caroline Frame, Email: [log in to unmask] Telephone: 029 207 43241
Dr Lesley Jones, Email: [log in to unmask] Telephone: 029 206 87054
Projects and Supervisors
- Inferring disease biology from genome-wide association data
o Peter Holmans, Andrew Pocklington
- Investigating the genetic and phenotypic relationships of Bipolar Disorder
o Marian Hamshere, Ellie Russell, Nick Craddock
- Exploring genetic variation and risk of psychosis during adolescence in the ALSPAC birth cohort
o Stan Zammit, Valentina Moskvina
- Identification of functional components associated with disease risk
o Andrew Pocklington, Peter Holmans, Richard White (COMSI), Alun Preece (COMSI)
- Investigating the mechanisms of cholesterol metabolism in Alzheimer's disease
o Lesley Jones, Denise Harold, Julie Williams
- The molecular genetics of myoclonus-dystonia syndrome
o Derek Blake, Huw Morris
- The Identification of Protein Networks that contribute to Late-onset Alzheimer's Disease
o Julie Williams, Richard Abraham
- An investigation of de novo occurring sub-microscopic chromosomal abnormalities in the aetiology of schizophrenia
o George Kirov, Mike Owen
- Heterogeneity in psychiatric outcomes in children of depressed adults.
o Stephan Collishaw, Anita Thapar
- Investigating the genetic mechanisms of immunological abnormalities in Alzheimer's disease
o Lesley Jones, Claire Harris, Paul Morgan, Mike Owen
- Imprinted genes, impulsive behaviour and risk-taking
o Anthony Isles, Trevor Humby (PSYCH)
- Genetic and Neural Vulnerability to Impulse Control Disorders in Parkinson's disease
o Huw Morris, Nigel Williams, Andrew Lawrence (PSYCH)
- Heritability of functional brain responses to emotional stimuli
o Xavier Caseras, Richard Wise (CUBRIC)
- Relations between cognition and the development of substance abuse in adolescence
o Marianne van den Bree, Marcus Munafo (Bristol), Stephanie van Goozen (PSYCH), Jon Heron (ALSPAC)
- Connectivity of memory networks in ageing and early memory decline
o Mike O'Sullivan (Psych), Richard Wise (CUBRIC), Derek Jones (CUBRIC)
Dr. Marian L. Hamshere
Statistical Geneticist
BBU/Department of Psychological Medicine
Cardiff University
Cardiff
CF14 4XN
UK
See our PhD opportunities for 2010
http://www.cf.ac.uk/medic/irg-neur/phdprojects/index.html
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