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CCP4BB  December 2009

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Subject:

Postdoctoral position at Structural Bioinformatics Laboratory, Turku, Finland

From:

Tiina Salminen <[log in to unmask]>

Reply-To:

Tiina Salminen <[log in to unmask]>

Date:

Tue, 29 Dec 2009 12:24:38 +0200

Content-Type:

text/plain

Parts/Attachments:

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text/plain (54 lines)

POST-DOCTORAL POSITION AVAILABLE at Structural Bioinformatics  
Laboratory, Abo Akademi University (Turku, Finland)  
http://web.abo.fi/fak/mnf/bkf/research/sbl/

Project: Structural basis for ligand recognition by copper amine oxidases

The project focuses on structural and functional studies of human  
vascular adhesion protein-1 (hAOC3), which belongs to the  
semicarbazide-sensitive amine oxidases/copper containing amine  
oxidases (SSAOs/CAOs E.C. 1.4.3.6). hAOC3 is involved in the leukocyte  
trafficking at the sites of inflammation and in glucose uptake. hAOC3  
is a target for drug discovery and its roles in inflammatory  
conditions are relatively well studied but very little is known about  
its physiological substrates and interactions at molecular level. The  
aim of the project is to find out the structural determinants for the  
unique substrate specificity and physiological interactions of hAOC3.

Required qualifications:
Applicants are expected to have:
- a PhD degree or shortly receive one
- a good knowledge of protein structure
-experience in protein expression, purification, crystallization, data  
collection and structural analysis of macromolecules

Experience in structural bioinformatics is of advantage (sequence  
alignments, modelling, phylogenetics, and ligand docking). Candidates  
do not need to fulfil all qualifications but experience in some of the  
above listed areas is essential. Since the project is done in  
collaboration with a PhD student and several external collaborators  
the applicant should enjoy working in a collaborative environment.

Duration: 4-years (funded by Academy of Finland)

Application:
Respond with a brief statement describing expertise and research  
interests, a CV, and contact information of one reference (or letter  
of recommendation) by e-mail to [log in to unmask]
Review of applications will begin immediately and continue until the  
position is filled. Candidates are encouraged to send applications  
before 10.1.2010.
Applicants will be evaluated based on qualifications and suitability  
for the project.


-- 
Tiina Salminen, PhD,
Adjunct professor in Structural biochemistry

Senior lecturer, Biosciences
Department of Biochemistry and Pharmacy
Abo Akademi University
Tykistökatu 6A
FIN-20520 Turku
Finland

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