JiscMail Logo
Email discussion lists for the UK Education and Research communities

Help for ACB-CLIN-CHEM-GEN Archives


ACB-CLIN-CHEM-GEN Archives

ACB-CLIN-CHEM-GEN Archives


ACB-CLIN-CHEM-GEN@JISCMAIL.AC.UK


View:

Message:

[

First

|

Previous

|

Next

|

Last

]

By Topic:

[

First

|

Previous

|

Next

|

Last

]

By Author:

[

First

|

Previous

|

Next

|

Last

]

Font:

Proportional Font

LISTSERV Archives

LISTSERV Archives

ACB-CLIN-CHEM-GEN Home

ACB-CLIN-CHEM-GEN Home

ACB-CLIN-CHEM-GEN  December 2009

ACB-CLIN-CHEM-GEN December 2009

Options

Subscribe or Unsubscribe

Subscribe or Unsubscribe

Log In

Log In

Get Password

Get Password

Subject:

Re: Some weird and wonderful tests

From:

Joan Pearson <[log in to unmask]>

Reply-To:

Joan Pearson <[log in to unmask]>

Date:

Tue, 22 Dec 2009 15:04:05 +0000

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (226 lines)

I recall a discussion with a practice nurse about a request for an unusual clutch of expensive (but orthodox) tests, some of which required special collection arrangements.  It was unclear what the clinical reasons were and I suggested that the GP should refer the patient to the appropriate consultant, who would then request appropriate tests.

She said "Oh, these tests have been requested by a consultant", so I asked for the specialty. 

 "A consultant trichologist" she said   

Dr MJ Pearson
Department of Clinical Biochemistry & Immunology
Old Medical School
Leeds General Infirmary (Leeds Teaching Hospitals NHS Trust)
LEEDS LS1 3EX
UK

tel   (44)-[0]113-392-3945
fax  (44)-[0]113 392-3453.

http://www.leedsth.nhs.uk


>>> IAN WATSON <[log in to unmask]> 22/12/2009 13:51 >>>
This is a clear case of gobbaldygookitis the most marked symptom is
willingness to believe anything and has the marked side-effect of
reducing your bank balance in a reciprocal relationship to your
hypochondria!

Dr Ian D Watson

Consultant Biochemist & Toxicologist

Dept Clinical Biochemistry

University Hospital Aintree

Lower Lane

Liverpool

L9 7AL

Tel +44 151 529 3575

Fax +44 151 529 3310

 

Fundamentals of Analytical Toxicology recently published:
http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0470319356.html 

 

 

 

 

 

________________________________

From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of Jones Alison
Sent: 22 December 2009 13:44
To: [log in to unmask] 
Subject: Re: Some weird and wonderful tests

 

I should have made it clear that the GP isn't being asked to treat the
patient on the basis of these results - the private hospital which asked
for them will follow her up.

 

The GPs concern (and mine) is whether neither of us know anything about
the tests because they are 'quack' medicine or because they are at the
cutting edge of scientific investigation.  She phoned me because she
wants to know what she should be saying to her patient as the patient is
now booked in for a 5 day stay at this hospital for futher
investigation, at not inconsiderable expense.

 

The overwhelming response from the mailbase so far is that there is
probably very little clinical utility in these tests.  Is that just
because no-one has heard of any of the tests and as we are the
'experts', if we haven't heard of them, they can't be any good?   I
would be interested to hear from anyone who does know anything about
this field of biochemistry to counterbalance the arguement.

 

And I don't know which laboratory the tests were performed in.

 

Thanks for all you help

 

Alison

	-----Original Message-----
	From: Clinical biochemistry discussion list
[mailto:[log in to unmask]]On Behalf Of Jones Alison
	Sent: 22 December 2009 12:34
	To: [log in to unmask] 
	Subject: Some weird and wonderful tests

	To the collective ACB Mailbase brain
	
	I have been contacted by one of our GPs this morning who has a
patient being investigated at a private hospital for ?ME.  They have
perfomed a panel of tests - some of which neither the GP nor myself have
heard of, or at least have no idea how to interpret.  Can anyone help me
out with indications and significance of any of the following?
	
	* Lymphocyte sensitivity test.  The patient showed definite
sensitivities to aluminium, formaldehyde and salicylate.  Borderline
sensitivity to petrol exhaust and metabisulphite.  Intracellular calcium
was high at 315 nmol/L

	* DNA Adducts (genomic DNA from leucocytes) investigation
implicated aluminium (sulphate) and methyresorcinol.  DNA-assocaited
Zinc was normal

	 

	* Cardiolipin studies in mitochondrial membranes showed some
blocking of the manganese sites on CL-synthase by calcium but not
significantly lowering CL synthesis.  Mild reduction in ion-gating
efficiency.

	 

	I could go on.  If anyone knows anything about these areas of
biochemistry, or has any thought or feelings about their clinical
utility, and is kind enough to get in touch with me directly, I may then
pick your brain further about some of the other investigations performed
on this patient.  I hope the private hospital investigating this patient
will write to her GP with a bit more clarity / direction when they have
completed their investigations, but in the meantime, the GP has no idea
what to say to / do with her patient.  

	 

	Any help greatly appreciated

	 

	Alison Jones

	Principal Clinical Biochemist 
	Kettering General Hospital 
	01536 493385 

	 

	 

	
	
	

	------ACB discussion List Information-------- This is an open
discussion list for the academic and clinical community working in
clinical biochemistry. Please note, archived messages are public and can
be viewed via the internet. Views expressed are those of the individual
and they are responsible for all message content. ACB Web Site
http://www.acb.org.uk List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions
(How to leave etc.) http://www.jiscmail.ac.uk/ 

------ACB discussion List Information-------- This is an open discussion
list for the academic and clinical community working in clinical
biochemistry. Please note, archived messages are public and can be
viewed via the internet. Views expressed are those of the individual and
they are responsible for all message content. ACB Web Site
http://www.acb.org.uk List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions
(How to leave etc.) http://www.jiscmail.ac.uk/ 
************************************************************************
*******
This email is confidential  and intended solely  for the use of the
individual
to  whom  it  is  addressed.  Any views or opinions  presented are
solely those
of the author and do not necessarily represent  those of  the
Organisation. If
you are not the  intended   recipient,  be  advised  that   you  have
received
this  email in  error  and  that  any  use, dissemination, forwarding,
printing
or copying  of this  email is  strictly  prohibited. If  you have
received this
email in  error  please  notify  the  sender.  This  e-mail  has  been
checked
for  viruses  using  anti-virus  software  



------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk 
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html 
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/

------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/

Top of Message | Previous Page | Permalink

JiscMail Tools


RSS Feeds and Sharing


Advanced Options


Archives

August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013
October 2013
September 2013
August 2013
July 2013
June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
2006
2005
2004
2003
2002
2001
2000
1999
1998


JiscMail is a Jisc service.

View our service policies at https://www.jiscmail.ac.uk/policyandsecurity/ and Jisc's privacy policy at https://www.jisc.ac.uk/website/privacy-notice

Secured by F-Secure Anti-Virus CataList Email List Search Powered by the LISTSERV Email List Manager