we are performing a VROI analysis on normalized brain PET scans.
We are planning to explore both anatomical (gyri, lobules) and "cytoarchitectonical" (Brodmann areas) VROIs obtained from the Pickatlas tool of SPM and saved in analyze format for the further external use.
We are ok with the anatomical VROIs while we have some doubts about the Brodmann areas VROIs.
We are afraid that the default way in which they are drawn could be too "thin" as compared to the PET scanner resolution (thus causing partial volume effect problems).
We noticed that increasing the option "dilate" in the graphical user interface from the default 0 (zero) to 1 or 2, the VROI becomes thicker. In our opinion, with "dilate" 2.5 or 3 the VROIs obtained seem to be more reasonable to avoid big partial volume effect problems.
Nevertheless this choice could be wrong or arbitrary, so we'd like to ask to the wfu_Pickatlas and SPM experts which is the more appropriate (and less arbitrary) choice in this case.
Moreover we did not fully understand which is effect of choosing 2D or 3D option before selecting the VROI.
Thanks in advance for your help