Depending on your definition of 'identical', examples of repeated gene
duplication contribute to these:
You could look at glyoxalases where there are dimeric examples where
each monomer is composed of a repeated subdomain (A1-A2:A1-A2) and
monomeric examples where a further duplication has occurred (A1-A2-A3-A4)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1169964
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1217405
There are also a number of nucleic acid binding proteins which have
strings of domains (e.g. zinc finger or RRM domains)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1217405
http://www.ncbi.nlm.nih.gov/pubmed/9305981
Depending on your definition of 'domain', pretty much every
repeat-protein (e.g. TPR, WD40 etc) could fall under this category.
Cheers,
Charlie
Shankar Prasad Kanaujia wrote:
> Dear CCP4 users,
> Is there any multi-domain protein (with at least two domains) which has
> identical tertiary structure of each domain ?
>
> Thanking you.
>
> -regards
> shankar
>
>
--
Charlie Bond
Professorial Fellow
University of Western Australia
School of Biomedical, Biomolecular and Chemical Sciences
M310
35 Stirling Highway
Crawley WA 6009
Australia
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