> expressing, purifying and crystalizing the protein
They are also useful. The NIH PSI initiative for example is trying as
a part of their Protein Structure Knowledgebase to establish a material
repository.
How well this will be generally accepted is another question, and the
storage and retrieval
problem is even more formidable than the comparatively simple storage of
images.
http://kb.psi-structuralgenomics.org/KB/index1.jsp?pageshow=37
The time for such material and data repositories certainly has come. But
even
simple tasks such as analyzing and data-mining all crystallization data from
all centers are still not readily possible. Others and myself pointed this
out
over the years in various publications - for example emphasizing consistent
metrics
etc etc, but not much has changed. It is an enormous loss of opportunity for
information gain, just as neglecting diffraction images. The issue of
standardization
is in most situations a very difficult one. Just see the multitude of
opinions on the ccp4bb.....
BR
-----Original Message-----
From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of Liz
Potterton
Sent: Wednesday, March 18, 2009 10:17 AM
To: [log in to unmask]
Subject: Re: [ccp4bb] images
Dear CCP4BB,
For further research of a particular structure wouldn't hints on
expressing, purifying and crystalizing the protein often be more
useful than images or amplitudes?
Liz
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