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FSL  October 2008

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Subject:

Re: sigma, SNR, standarderror, standarddeviation, etc.

From:

Ivana Drobnjak <[log in to unmask]>

Reply-To:

FSL - FMRIB's Software Library <[log in to unmask]>

Date:

Tue, 14 Oct 2008 16:04:33 +0100

Content-Type:

text/plain

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text/plain (99 lines)

Hello,

the formula SNR = meanint/std(noise) is the correct one.  The SNR in  
the noise-file is 2 times weaker than the one you want originally due  
to that error in the script I mentioned in the previous e-mail.   
Until I fix this, the best is to specify sigma instead of SNR when  
you are running POSSUM (sigma = 64*required_sigma - this is due to  
POSSUM processing which I explained in the previous e-mail).  You can  
calculate the required_sigma as meanint/SNR.  The meanint calculate  
from the generated image to which no noise is added.

The output image will have std(noise)=required_sigma and SNR=meanint/ 
required_sigma. Ignore the noise-file until it is fixed.

Best,
Ivana



On 14 Oct 2008, at 09:18, Bjorn Roelstraete wrote:i

> Dear Ivana,
>
> Thank you for clearing that out. However, if i use my numbers (I  
> get them from the noise-file that is created after running possum)  
> with your formula, it looks like SNR = meanint/128*sigma instead of  
> SNR = meanint/64*sigma. For example 10 = 33.58/128*.026236 and 20 =  
> 33.58/128*.013118 and so on. On the other hand, if i subtract the  
> noise image from the no_noise image and calculate the std, I do get  
> 64*.026236= 1.67. So it looks as if the formula would have to be  
> SNR = meanint/2*std(noise).
>
> Bjorn
>
> Ivana Drobnjak wrote:
>> Dear Bjorn,
>> Sigma is the standard deviation of the noise (std(noise)), SNR is  
>> SNR=meanint/std(noise) . meanint is calculated over the brain  
>> voxels and ingnoring the background.
>> However,  I think you have spotted an inaccuracy  in POSSUM GUI  
>> and scripts regarding the noise specification and SNR. Sigma in  
>> the GUI is 64 times (dimX) smaller than the sigma of the output.   
>> This extra number is due to the fact that the noise is originally  
>> added to the raw signal which is than converted into the image  
>> using FFT and that scalar is needed.  So sigma that you specify in  
>> the GUI (or in case you specify the SNR)  does not correspond to  
>> the actual sigma of the output (which you should by the way  
>> calculate using fslstats -s option from the  image you obtain by  
>> subtracting the noise and nonoise image).
>> I will fix this asap so that the terminology is consistent.  
>> Meantime, the best is not to use the SNR option but to specify   
>> 64*required_sigma when you are running POSSUM. You can calculate  
>> the required_sigma as meanint/SNR.  The meanint calculate from the  
>> generated image to which no noise is added.
>> Hope this helps,
>> Ivana
>> On 13 Oct 2008, at 13:21, Bjorn Roelstraete wrote:
>>> Dear list,
>>>
>>> In Possum there are 2 ways of specifying the noise level. You can  
>>> add thermal noise with a certain SNR, or you can specify a value  
>>> for sigma. Can someone explain the relationship between SNR,  
>>> sigma, mean intensity, etc?
>>> In my case, with a specified SNR of 20, i get a sigma of . 
>>> 01311808984375000000 with a medintensity of 33.582310. For a SNR  
>>> of 10, i get a sigma of .02623617968750000000 with a medintensity  
>>> of 33.582310. When i calculate the standarddeviation of the  
>>> image, i get 5.01, so clearly sigma != stdv. What is the  
>>> difference between them? How are they related? And most  
>>> importantly, how are they calculated?
>>>
>>> The literature is very vague on this issue. For example, in one  
>>> article i found that SNR = (meanintensity activation -  
>>> meanintensity rest)/standarderror noise. Is this correct? If so,  
>>> is this on the voxel, ROI or image level? Also, what is the  
>>> relation between my standard deviation (as calculated with  
>>> fslstats), the standarderror of the noise  (whatever that is) and  
>>> sigma as specified in Possum?
>>>
>>> Many thanks,
>>>
>>> -- 
>>> Bjorn Roelstraete
>>> Ghent University
>>> Department of Data-analysis
>>> H. Dunantlaan 1, B-9000 Gent, Belgium
>>> Tel: 32-9-2646434
>>> E-mail: [log in to unmask]
>>>
>
> -- 
> Bjorn Roelstraete
> Ghent University
> Department of Data-analysis
> H. Dunantlaan 1, B-9000 Gent, Belgium
> Tel: 32-9-2646434
> E-mail: [log in to unmask]
>

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