thanks a lot for your help, however, I still have a couple of questions:
>> I have a couple of questions regarding the normalisation step in SPM5 using
>> the Unified Segmentation procedure: - Is the procedure to (1) Co-Register
>> EPI and anatomical T1 of the subject, (2) Normalise the T1 of the subject
>> with a template delivered with SPM (T1.mnc?) (3) To apply the parameters
>> derived from this normalisation to the EPIs. Is that correct or am I
>> missing something?
> If you use Unified Segmentation, then at no point does the algorithm use any
> of the usual template images. The matching is done entirely with the three
> tissue probability maps in the tpm directory.
Sorry, my mistake, I was aware about this difference. However, I'm still not sure whether this is the correct procedure:
1. "Coregister" T1 of the subject to the EPIs of the subject
2. "Segment" the T1 of the subject including normalisation
3. "Normalise" the EPIs by applying the matrix generated by step 2
> This paper may be of interest here:
> Crinion J, Ashburner J, Leff A, Brett M, Price C, Friston K. (2007). "Spatial
> normalization of lesioned brains: Performance evaluation and impact on fMRI
> analyses". NeuroImage 37(3):866--875
Thanks a lot, this paper was very helpful and informative
A question regarding this paper: The regularisation manipulated in the paper was the "Bias Regularisation" in he SPM5-Segment options, is that correct? If that is right, which are the according regularisation levels in SPM5? Light-Medium-Heavy?
Again, thanks a lot &