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ALLSTAT  August 2008

ALLSTAT August 2008

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Subject:

STATISTICIAN FOR EARLY CLINICAL DEVELOPMENT

From:

Markus Abt <[log in to unmask]>

Reply-To:

Markus Abt <[log in to unmask]>

Date:

Fri, 22 Aug 2008 07:43:51 +0100

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (47 lines)

Headquartered in Basel, Switzerland, Roche is one of the world’s leading 
research-focused healthcare groups in the fields of pharmaceuticals and 
diagnostics.  At our development site in the United States in Nutley, New we 
are currently looking for statisticians to support our newly formed department 
of Biomathematics.

The successful candidates will provide high level statistical support to drug 
projects in the early phases of clinical development within one or several 
Disease Biology Areas. On project level teams you will engage in strategic 
discussions regarding the early clinical development of a compound even 
before entry into man and contribute to clinical development plans. You will 
also be responsible for early clinical development studies (entry into human 
studies, experimental medicine studies, Proof of Concept, Proof of Mechanism 
studies, etc) as well as all clinical pharmacology studies during the life cycle of 
the compound. In close collaboration with statistical programmers and other 
statisticians you lead the efforts to ensure that the results of statistical and 
other analyses are of high quality and available in time to support decision 
making of the project teams. Strong analytical skills allow you to advice teams 
on the correct interpretation of data from various types of experiments. You 
contribute to the writing of protocols as well as clinical study reports and you 
participate in health authority interactions during the early phases of drug 
development. Practical experience in a wide variety of statistical 
methodologies will enable you to contribute to the development of innovative 
study designs and new techniques for data analyses.

Who you are:
Minimum: 
(*) University Education (MSc or PhD) in Statistics or a very similar area. 
(*) Proven experience in statistical data analyses in the life sciences and in 
communicating statistical principles to non-statisticians. 
(*) Experience in using statistical software (SAS and/or S-Plus/R). 
(*) Communicates clearly and effectively in written reports, data 
presentations and meetings as required. 
(*) Fluent in English, written and spoken.

Desired: 
(*) Several years of experience working as a statistician in early or late 
phases of clinical drug development in a pharmaceutical environment. 
(*) Strong and proven interest in the application and development of new 
statistical methodologies. Experience in practical applications of Bayesian 
Statistics or adaptive designs would be an asset. 
(*) Experience in working in an interdisciplinary and international environment.

If you are interested in this challenging opportunity, please apply online at our 
website http://careers.roche.com.  The posting corresponding to the 
described opportunity entitled  “STATISTICAL LEADER - PHARMA 
DEVELOPMENT”.  Only applications made on-line can be considered.  

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