Principal Statistician/Statistics Manager
West London, UK
Req No.: 46109

Basic Qualifications
With an MSc in Statistics (or equivalent), you will have extensive 
experience working as a statistician within a pharmaceutical setting. Your 
experience should include use of a broad range of statistical techniques, 
preparation of Reporting and Analysis Plans (RAP), Reporting and Analysis 
of clinical trials using SAS, protocol design, sample size calculation and 
protocol development, NDA/MAA submissions. You will have demonstrated 
experience supporting or preferably, providing statistical leadership in 
the development of medicines, with a proven track record of working 
effectively internationally and across the functional boundaries and in 
the matrix. You will also have demonstrated an ability to make an impact 
within a cross-functional team, and wide understanding of clinical 
development processes.

Preferred Qualifications
Ideally you will have experience of leading the planning of the work in a 
complex and/or multi-disciplinary area, and working flexibly across a 
broader spectrum of activities. You will have demonstrated experience of 
being highly influential in multi-disciplinary teams. A good understanding 
of the regulatory processes and experience of influencing regulatory 
agencies on key statistical issues would be desirable. Previous experience 
of the Inflammation therapeutic area, in particular rheumatoid arthritis, 
would be beneficial.

Details
GlaxoSmithKline is one of the world's leading pharmaceutical and 
healthcare companies, with statisticians and programmers working in 
Research and Development at UK and US sites. The vacancy is for an 
experienced statistician to support the development of new drugs, 
including targeted therapies in the Inflammation portfolio. 

As a member of a team of skilled and committed statisticians and 
programmers, you will use your statistical expertise to contribute to the 
design and analysis of Phase II-IV clinical trials, interpretation of 
results, and subsequent use of the results for regulatory submissions and 
publications. You may also research innovative statistical methodologies 
for study design and analysis to enhance clinical development strategies. 
Working closely with (US and UK based) physicians, clinical research 
scientists, regulatory colleagues and data managers you will utilise your 
excellent team-working and planning skills to provide quality input into 
international clinical development programmes. 

The roles requires hands-on involvement in study design, CRF development, 
statistical analysis plan creation, statistical programming, 
interpretation of results, review of study reports, preparation of 
manuscripts, abstracts and promotional materials. The more experienced 
role will be a Project Statistician role and you will be a key member of a 
global multi-disciplinary team so you will need to influence colleagues in 
complex situations and make an impact within a cross-functional team-based 
environment.

When applying for this role, please use the 'cover letter' of the on-line 
application or your CV to describe how you meet the competencies for this 
role, as outlined in the job requirements above. Thank you for your 
interest in this opportunity. The information that you have provided in 
your cover letter and CV will be used to assess your application. 

To Apply: 
At GlaxoSmithKline we provide a supportive working environment, and a 
range of development challenges and opportunities. We also offer 
competitive benefits and compensation packages designed to attract and to 
retain the very best.  For confidential consideration and efficient 
processing, please apply online via our career pages at www.gsk.com.  
Enter requisition number 46109 to be taken directly to this vacancy.