Dear Raj,
>Put another way: nobody ever runs a small-volume correction
>on regions of the T-map that look as if they are probably empty.
Oh yes we do. For example, as epileptologists we're pretty often
interested in the hippocampus - that's about four resels, not 500, and
we'll correct accordingly. Obviously I won't care what the T-map looks
like in the area - as I won't look at it before setting up the analysis.
>But if the validity of the procedure hinges upon pre-stating
>hypotheses and then acting on them regardless of how the data look,
>then that is what people should be doing, no?
If you were interested in say the calcarine fissure and post hoc found
something on your T-map in the hippocampus it would make no sense
whatsoever to "correct" for that region of no prior hypothesis - the ARW
365 numberplate example.
ATB, A
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