Dear All
I am assigning a dimer which in its unbound state has two fold
symmetry. However, once I bind a ligand to it some of the symmetry (but
not all) is lost. Thus I end up with peaks in my 1H-15N hsqc some of
which are for A subunits and some of which are for B and some of which
are for A and B. In the case of the A+B peaks degenerate peaks should
each pair orf resonances from the two two dimensions and a sigle chain
be in separate peakContribs....
Also another question which is related. Programmatically what is the
quickest way to identify sets of identical chains in a molecular system?
Do I need to do a sequence comparison ever time I search for a repeat of
the same chain...
regards
gary
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Dr Gary Thompson
Astbury Centre for Structural Molecular Biology,
University of Leeds, Astbury Building,
Leeds, LS2 9JT, West-Yorkshire, UK Tel. +44-113-3433024
email: [log in to unmask] Fax +44-113-2331407
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